Magnesium Sulphate Is A Pill

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MAGNESIUM SULPHATE

The efficacy of magnesium sulphate as an anticonvulsant has been the subject of clinical studies. It is a commonly used medication in the treatment of pregnancy-induced hypertension. It is employed to reduce blood pressure, treat pre-eclampsia and eclampsia, and is also utilised in the treatment of preterm labour.

Drug interactions] Drugs contraindicated with magnesium sulphate include polymyxin B sulphate, streptomycin sulphate, calcium gluconate, dobutamine hydrochloride, procaine hydrochloride, tetracycline, penicillin, and nafcillin (ethylated naphthylpenicillin).

[Adverse Reactions

1 Intravenous injection of ITS often cause flushing tie-up, sweating, dry mouth and other symptoms, rapid intravenous injection can cause nausea, vomiting, panic, dizziness, individual nystagmus, slow down the speed of injection symptoms can disappear.

2 Renal insufficiency, large doses of drugs, blood magnesium accumulation can occur, blood magnesium concentration of 5mmoi / L, there can be muscle excitability inhibition, sensory response is slow, knee tendon reflexes disappeared, respiration began to be inhibited, blood magnesium concentration of 6mmol / L, respiratory arrest and arrhythmia, cardiac conduction block, the concentration of further increase, the heart can be stopped.

3 Continuous use of magnesium sulfate can cause constipation, some patients can appear paralytic intestinal obstruction, after stopping the drug improved.

4 Very few blood calcium decrease, reproduce hypocalcaemia.

5 Magnesium ions can freely pass through the placenta, resulting in neonatal hypomagnesemia, manifested as low muscle tone, poor sucking power, inactivity, inaudible cry, etc., and a few have respiratory depression.

6 A few pregnant women develop pulmonary oedema.

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