United Home Sodium Bicarbonate

United home sodium bicarbonate

Specification

Adding sodium bicarbonate to water can prepare a solution with specific pH adjustment ability, which may have benefits in terms of health, hydration, and exercise performance, but attention should be paid to its safety and compatibility.

Application

Sodium bicarbonate, as a systemic alkalizing agent, increases the concentration of bicarbonate in plasma, buffers excessive hydrogen ion concentration, raises blood pH, and thus reverses the clinical manifestations of acidosis.

Dosage Forms and Strengths

NaHCO₃ comes in various forms, including oral tablets, IV injections, and IV infusions. Oral formulations are available via 325 mg powder and 650 mg oral tablets. One mEq NaHCO₃ is 84 mg. One gram of NaHCO₃ contains 11.9 mEq of sodium and bicarbonate ions. One 650 mg tablet of NaHCO₃ has 7.7 mEq of sodium and bicarbonate ions.

The 2 primary IV injection formulations of NaHCO₃ are:

7.5% concentration = 44.6 mEq NaHCO₃ in 50 mL. This concentration supplies 75 mg/mL of 0.9 mEq/mL each of sodium and bicarbonate.

8.4% concentration = 50 mEq in 50 mL. This concentration supplies 84 mg/mL of 1 mEq/mL for each sodium and bicarbonate. One ampoule of 50 mL contains 50 mEq sodium and 50 mEq bicarbonate to a total of 100 mEq/50 mL and corresponds to 2000 mOsm/L. This formulation is a hypertonic solution that can raise serum sodium concentration by attracting water to the extracellular areas from the intracellular space.

A 4.2% and 5% solution are also available, though not as often used.

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