Magnesium Sulphate Paste Pregnancy

MAGNESIUM SULPHATE

Magnesium sulfate is used in pregnancy primarily for specific medical conditions. It is a medication that can be used to prevent seizures in women with preeclampsia, a condition characterized by high blood pressure during pregnancy, and for fetal neuroprotection in cases of extreme prematurity.

When used in pregnancy, magnesium sulfate must be administered with caution. Intravenous use beyond 5 to 7 days can potentially cause fetal abnormalities, and continuous IV infusion, especially more than 24 hours before delivery, can result in magnesium toxicity in the newborn, including neuromuscular or respiratory depression . It is also advised to avoid its use in the 2 hours before delivery unless it is the only therapy available for eclamptic seizures. The medication readily crosses the placenta and can affect the fetus, with potential issues such as hypocalcemia, skeletal demineralization, and congenital rickets reported with continuous maternal administration for more than 5 to 7 days .

For breastfeeding mothers, the safety of magnesium sulfate has not been established, and it should only be used if clearly needed. Magnesium is excreted into human milk, and the concentration can be approximately twice that of maternal serum concentrations .

It is important to note that the use of magnesium sulfate paste for therapeutic purposes, such as treating skin conditions like boils or acne, is a separate application and not directly related to its use during pregnancy . However, the paste should not be used by pregnant women without medical advice, as the safety and effects of topical application during pregnancy are not clearly established.

In summary, while magnesium sulfate has important medical uses during pregnancy, it must be used under the guidance of healthcare professionals who are aware of the potential risks and benefits.

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