Magnesium Sulphate In Obstetrics

Magnesium Sulphate In Obstetrics

Another Name:Epsom salts
CAS Number:10034-99-8
EINECS:231-298-2
Chemical formula:MgSO4.7(H2O)
PACKING:25KG/BAG
Molecular weight:246.47
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Xiamen Ditai Chemicals Co., Ltd. is one of the most reliable manufacturers and suppliers of magnesium sulphate in obstetrics in China. Welcome to buy high quality chemical products at competitive price from our factory.

 

 

 

MAGNESIUM SULPHATE

 

 

Magnesium sulfate is an inexpensive drug, but setting up and monitoring infusions requires additional medical staff time. Despite its widespread use, particularly in the United States, its role as a tocolytic is not supported by strong evidence. However, its neuroprotective properties and effectiveness in treating preeclampsia and eclampsia are well recognized in obstetric practice.

 

 

 

 

ITEM

SPECIFICATION

Appearance White Small Granular
Purity 99.5%min
MgSO4

 48.59%min

MgO MgO
Mg Mg
PH 5-9

 

 

 

Neuroprotection in Preterm Infants: Magnesium sulfate is used to reduce the risk of cerebral palsy in infants born before 34 weeks of gestation. A Cochrane review concluded that antenatal MgSO4 therapy can decrease the risk of cerebral palsy in children born to women at risk of early preterm birth.

Treatment of Preeclampsia and Eclampsia: Magnesium sulfate is the preferred anticonvulsant for women with preeclampsia and eclampsia, helping to prevent and control eclamptic seizures.

Side Effects: Maternal side effects can include flushing, sweating, a sensation of warmth, nausea, vomiting, headache, palpitations, and rarely, pulmonary edema. Overdose can lead to cardiac and neurological adverse events, but there is no evidence of unintended adverse outcomes in the neonate.

Efficacy in Subgroups: MgSO4 is beneficial for fetal neuroprotection in both spontaneous and iatrogenic preterm births, with no significant differences in treatment effects among various subgroups, including those with pre-eclampsia, spontaneous preterm birth, and other related conditions.

Pharmacokinetics: The volume of distribution of magnesium can vary, but the plasma clearance is fairly consistent across populations. The minimum effective serum magnesium concentration for eclampsia prophylaxis is lower than the generally accepted therapeutic level.

 

 

 

 

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