Barium Sulphide in Medical Store Near Me

BARIUM SULPHATE

Barium sulphide (BaS) is an inorganic compound with limited but specialized applications in medicine and pharmaceuticals. Unlike its more widely used counterpart, barium sulphate (BaSO₄), which is inert and safe for internal use, barium sulphide is reactive and toxic due to its solubility and release of sulfide ions (S²⁻). However, under controlled conditions, it has niche uses in medical and laboratory settings. Below is a detailed examination of its role, safety concerns, and regulatory status.

Potential Medical and Pharmaceutical Uses.While not approved for direct therapeutic use due to toxicity, BaS has been explored in limited contexts: Depilatory Agents (Hair Removal)Mechanism: BaS reacts with water to form barium hydroxide (Ba(OH)₂) and H₂S, which breaks down keratin in hair.Historical Use:Early 20th-century depilatory creams contained BaS (now replaced by safer alternatives like calcium thioglycolate).Risks: Skin irritation, burns, and systemic toxicity if absorbed.Precursor for Barium Compounds:Used to synthesize barium sulfate (BaSO₄) for X-ray contrast agents.Production of barium peroxide (BaO₂), a disinfectant.Inorganic synthesis (e.g., sulfide-based reactions). Antimicrobial Properties (Limited Research) H₂S Release: Low concentrations of H₂S have been studied for antibacterial effects, but BaS itself is too hazardous for clinical use.Safety Concerns and Toxicity:Causes severe gastrointestinal damage, vomiting, and metabolic acidosis.Lethal dose (LD₅₀, oral, rats): ~50-100 mg/kg.Releases H₂S gas, leading to respiratory failure at high concentrations.Causes chemical burns and dermatitis.Soluble barium ions (Ba²⁺) interfere with potassium channels, causing muscle paralysis and cardiac arrhythmias.

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